Mouse Traf3ip1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Traf3ip1
Locus ID	74019
Kit Components	GA209676G1, Traf3ip1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209676G2, Traf3ip1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209676G3, Traf3ip1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_028718
Synonyms	3930402D05Rik; AU041749; MIP-T3
Summary	Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules (By similarity). Involved in epithelial morphogenesis and in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels (PubMed:26487268). Involved in ciliogenesis (PubMed:21945076).[UniProtKB/Swiss-Prot Function]

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