Mouse Ube2d2b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ube2d2b
Locus ID	73318
Kit Components	GA209455G1, Ube2d2b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209455G2, Ube2d2b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209455G3, Ube2d2b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001276397, NM_028502, NR_003639
Synonyms	1700013N18Rik
Summary	Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection (By similarity). Plays a role in early maturation of the testis.[UniProtKB/Swiss-Prot Function]

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