Mouse Vps50 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Vps50
Locus ID	73288
Kit Components	GA209446G1, Vps50 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209446G2, Vps50 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209446G3, Vps50 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001167750, NM_001167751, NM_024260
Synonyms	1700034M03Rik; 8430415E05Rik; BLM; C87205; Ccdc132; mKIAA1861
Summary	Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane. Within the EARP complex, required to tether the complex to recycling endosomes. Not involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).[UniProtKB/Swiss-Prot Function]

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