Mouse Ttc19 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ttc19
Locus ID	72795
Kit Components	GA209343G1, Ttc19 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209343G2, Ttc19 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209343G3, Ttc19 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_028360, NM_029704
Synonyms	2010204O13Rik; 2810460C24Rik; AI505442
Summary	Required for the preservation of the structural and functional integrity of mitochondrial respiratory complex III by allowing the physiological turnover of the Rieske protein UQCRFS1 (PubMed:21278747, PubMed:28673544). Involved in the clearance of UQCRFS1 N-terminal fragments, which are produced upon incorporation into the complex III and whose presence is detrimental for its catalytic activity (PubMed:28673544).[UniProtKB/Swiss-Prot Function]

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