Mouse Sass6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Sass6
Locus ID	72776
Kit Components	GA209339G1, Sass6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209339G2, Sass6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209339G3, Sass6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001289568, NM_001289571, NM_028349
Synonyms	2810453L12Rik
Summary	Central scaffolding component of the centrioles ensuring their 9-fold symmetry. Required for centrosome biogenesis and duplication: required both for mother-centriole-dependent centriole duplication and deuterosome-dependent centriole amplification in multiciliated cells (PubMed:24240477). Required for the recruitment of STIL to the procentriole and for STIL-mediated centriole amplification (By similarity).[UniProtKB/Swiss-Prot Function]

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