Mouse Lime1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Lime1
Locus ID	72699
Kit Components	GA209318G1, Lime1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209318G2, Lime1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209318G3, Lime1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_023684
Synonyms	2810038K19Rik; LIME
Summary	Involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and TCR (T-cell antigen receptor)-mediated T-cell signaling in T-cells. In absence of TCR signaling, may be involved in CD4-mediated inhibition of T-cell activation. Couples activation of these receptors and their associated kinases with distal intracellular events such as calcium mobilization or MAPK activation through the recruitment of PLCG2, GRB2, GRAP2, and other signaling molecules.[UniProtKB/Swiss-Prot Function]

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