Mouse Taf4b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Taf4b
Locus ID	72504
Kit Components	GA209256G1, Taf4b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209256G2, Taf4b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209256G3, Taf4b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001100449, NM_001369357, NM_001369358
Synonyms	105kDa; 2610524B04Rik; 4932409F03Rik; AW987595; Taf2c2; TAFII-105; TAFII105
Summary	Cell type-specific subunit of the general transcription factor TFIID that may function as a gene-selective coactivator in certain cells. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators asond repressors. TAF4B is a transcriptional coactivator of the p65/RELA NF-kappa-B subunit. Involved in the activation of a subset of antiapoptotic genes including TNFAIP3. Through interaction with OCBA/POU2AF1, acts as a coactivator of B-cell-specific transcription. Plays a role in spermiogenesis and oogenesis.[UniProtKB/Swiss-Prot Function]

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