Mouse Plcd3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Plcd3
Locus ID	72469
Kit Components	GA209245G1, Plcd3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209245G2, Plcd3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209245G3, Plcd3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_152813, NM_001361706
Synonyms	2610205J15Rik; mKIAA1964
Summary	Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow.[UniProtKB/Swiss-Prot Function]

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