Mouse Otud6b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Otud6b
Locus ID	72201
Kit Components	GA209150G1, Otud6b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209150G2, Otud6b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209150G3, Otud6b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_152812
Synonyms	2600013N14Rik; AU015433
Summary	Deubiquitinating enzyme that may play a role in the ubiquitin-dependent regulation of protein synthesis, downstream of mTORC1 (By similarity). May associate with the protein synthesis initiation complex and modify its ubiquitination to repress translation (By similarity). May also repress DNA synthesis and modify different cellular targets thereby regulating cell growth and proliferation (By similarity). May also play a role in proteasome assembly and function (By similarity).[UniProtKB/Swiss-Prot Function]

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