Mouse Nsun4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nsun4
Locus ID	72181
Kit Components	GA209142G1, Nsun4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209142G2, Nsun4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209142G3, Nsun4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_028142, NM_001369075, NM_001369076
Synonyms	2310010O12Rik; 2810405F18Rik; AI507900; Shtap
Summary	Involved in mitochondrial ribosome assembly. 5-methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA at position 911; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). Targeted to LSU by MTERFD2/MTERF4 and probably is involved in a final step in ribosome biogenesis to ensure that SSU and LSU are assembled. In vitro can methylate 16S rRNA of the LSU; the methylation is enhanced by MTERFD/MTERF4.[UniProtKB/Swiss-Prot Function]

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