Mouse Alkbh4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Alkbh4
Locus ID	72041
Kit Components	GA209071G1, Alkbh4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209071G2, Alkbh4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209071G3, Alkbh4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001347492, NM_028070, NM_001359414, NM_001359415, NM_001359416, NM_001359417
Synonyms	2010004B12Rik; Abj4
Summary	Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84' (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation (By similarity).[UniProtKB/Swiss-Prot Function]

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