Mouse Trmu activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Trmu
Locus ID	72026
Kit Components	GA209064G1, Trmu gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209064G2, Trmu gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209064G3, Trmu gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_028063
Synonyms	1110005N20Rik; 1600025P05Rik; AI314320; Trmt1
Summary	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.[UniProtKB/Swiss-Prot Function]

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