Mouse Esco2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Esco2
Locus ID	71988
Kit Components	GA209049G1, Esco2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209049G2, Esco2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209049G3, Esco2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_028039
Synonyms	2410004I17Rik; D030072L07Rik
Summary	Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during the S phase. Acetylates the cohesin component SMC3.[UniProtKB/Swiss-Prot Function]

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