Mouse Lypd6b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Lypd6b
Locus ID	71897
Kit Components	GA209004G1, Lypd6b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209004G2, Lypd6b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209004G3, Lypd6b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_027990
Synonyms	2310010M24Rik; AW049525
Summary	Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro acts on nAChRs in a subtype- and stoichiometry-dependent manner. Modulates specifically alpha-3(3):beta-4(2) nAChRs by enhancing the sensitivity to ACh, decreasing ACh-induced maximal current response and increasing the rate of desensitization to ACh; has no effect on alpha-7 homomeric nAChRs.[UniProtKB/Swiss-Prot Function]

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