Mouse Ints12 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ints12
Locus ID	71793
Kit Components	GA208950G1, Ints12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208950G2, Ints12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208950G3, Ints12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_027927
Synonyms	1110020M19Rik; 2810027J24Rik; 4930529N21Rik; A230056J18Rik; AI666778; int12; Phf22
Summary	Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.[UniProtKB/Swiss-Prot Function]

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