Mouse Pdgfd activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pdgfd
Locus ID	71785
Kit Components	GA208946G1, Pdgfd gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208946G2, Pdgfd gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208946G3, Pdgfd gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_027924, NM_001357397, NM_001357398
Synonyms	1110003I09Rik
Summary	Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing (By similarity). Has oncogenic potential and can induce tumor formation. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix.[UniProtKB/Swiss-Prot Function]

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