Mouse Map3k13 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Map3k13
Locus ID	71751
Kit Components	GA208924G1, Map3k13 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208924G2, Map3k13 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208924G3, Map3k13 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_172821
Synonyms	C130026N12Rik; LZK
Summary	Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B (By similarity).[UniProtKB/Swiss-Prot Function]

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