Mouse Mus81 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mus81
Locus ID	71711
Kit Components	GA208905G1, Mus81 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208905G2, Mus81 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208905G3, Mus81 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_027877, NR_153768, NR_153769
Synonyms	1200008A18Rik; AI182501; AW045863
Summary	Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.[UniProtKB/Swiss-Prot Function]

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