Mouse Tex19.2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tex19.2
Locus ID	70956
Kit Components	GA208677G1, Tex19.2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208677G2, Tex19.2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208677G3, Tex19.2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_027622
Synonyms	4921530G04Rik; Tex19b
Summary	May be required during spermatogenesis, probably by participating in the repression of retrotransposable elements and prevent their mobilization (Probable). With its paralog, Tex19.1, collaborates with the Piwi-interacting RNA (piRNA) pathway, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins. Interacts with Piwi proteins and directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements (PubMed:28254886).[UniProtKB/Swiss-Prot Function]

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