Mouse Ttll7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ttll7
Locus ID	70892
Kit Components	GA208657G1, Ttll7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208657G2, Ttll7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208657G3, Ttll7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001302957, NM_001302958, NM_027594, NM_001357217
Synonyms	1110049N09Rik; 4921517B04Rik; C630030B20; mTTLL7
Summary	Polyglutamylase which preferentially modifies beta-tubulin (PubMed:16901895, PubMed:17499049, PubMed:19152315). Mediates both ATP-dependent initiation and elongation of polyglutamylation of microtubules (PubMed:16901895, PubMed:19152315). Required for neurite growth; responsible for the strong increase in tubulin polyglutamylation during postnatal neuronal maturation (PubMed:16901895).[UniProtKB/Swiss-Prot Function]

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