Mouse Ints10 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ints10
Locus ID	70885
Kit Components	GA208653G1, Ints10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208653G2, Ints10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208653G3, Ints10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001293791, NM_001293792, NM_027590, NM_001359129
Synonyms	4921521J11Rik; AI462004
Summary	Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex.[UniProtKB/Swiss-Prot Function]

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