Mouse Prdm5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Prdm5
Locus ID	70779
Kit Components	GA208616G1, Prdm5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208616G2, Prdm5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208616G3, Prdm5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_027547, NM_029549
Synonyms	4432417F03Rik; 6530401I24Rik; AI197291; E130112L17Rik; PFM2
Summary	Sequence-specific DNA-binding transcription factor. Represses transcription at least in part by recruitment of the histone methyltransferase EHMT2/G9A and histone deacetylases such as HDAC1. Regulates hematopoiesis-associated protein-coding and microRNA (miRNA) genes (By similarity). May regulate the expression of proteins involved in extracellular matrix development and maintenance, connective tissue components and molecules regulating cell migration and adhesion. May cause G2/M arrest and apoptosis in cancer cells (By similarity).[UniProtKB/Swiss-Prot Function]

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