Mouse Arhgap45 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Arhgap45
Locus ID	70719
Kit Components	GA208602G1, Arhgap45 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208602G2, Arhgap45 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208602G3, Arhgap45 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001142701, NM_001347074, NM_027521
Synonyms	6330406L22Rik; AW539505; Ha-1
Summary	Contains a GTPase activator for the Rho-type GTPases (RhoGAP) domain that would be able to negatively regulate the actin cytoskeleton as well as cell spreading. However, also contains N-terminally a BAR-domin which is able to play an autoinhibitory effect on this RhoGAP activity.[UniProtKB/Swiss-Prot Function]

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