Mouse Ints2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ints2
Locus ID	70422
Kit Components	GA208514G1, Ints2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208514G2, Ints2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208514G3, Ints2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_027421, NM_001363129, NM_001363130
Synonyms	2810417D08Rik; AA408260; AI987735; mKIAA1287
Summary	Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.[UniProtKB/Swiss-Prot Function]

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