Mouse Reep6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Reep6
Locus ID	70335
Kit Components	GA208479G1, Reep6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208479G2, Reep6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208479G3, Reep6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001204931, NM_139292
Synonyms	0610011M24Rik; Dp1l1
Summary	Required for correct function and survival of retinal photoreceptors (PubMed:24098485, PubMed:24691551, PubMed:28475715). Required for retinal development (PubMed:28369466). In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis (PubMed:28475715). May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane (PubMed:24098485, PubMed:28369466).[UniProtKB/Swiss-Prot Function]

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