Mouse Lypd8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Lypd8
Locus ID	70163
Kit Components	GA208440G1, Lypd8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208440G2, Lypd8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208440G3, Lypd8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001083884, NM_027339
Synonyms	2210415F13Rik
Summary	This gene encodes a member of the Ly6/PLAUR family of cysteine-rich proteins that plays an important role in the protection of colonic epithelium from flagellated microbiota. The encoded protein undergoes proteolytic processing to generate a mature, glycosylphosphatidylinositol-anchored protein that is localized to the apical surface of the colonic epithelial cells. Mice lacking the encoded protein are sensitive to chemically induced intestinal inflammation. [provided by RefSeq, Aug 2016]

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