Mouse Smc4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Smc4
Locus ID	70099
Kit Components	GA208423G1, Smc4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208423G2, Smc4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208423G3, Smc4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_133786, NM_001356976
Synonyms	2500002A22Rik; C79747; SMC-4; Smc4l1
Summary	Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity).[UniProtKB/Swiss-Prot Function]

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