Mouse Rsc1a1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rsc1a1
Locus ID	69994
Kit Components	GA208390G1, Rsc1a1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208390G2, Rsc1a1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208390G3, Rsc1a1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_023544
Synonyms	1700027M01Rik; OTTMUSG00000010365; Rs1
Summary	Mediates transcriptional and post-transcriptional regulation of SLC5A1. Inhibits a dynamin and PKC-dependent exocytotic pathway of SLC5A1. Also involved in transcriptional regulation of SLC22A2. Exhibits glucose-dependent, short-term inhibition of SLC5A1 and SLC22A2 by inhibiting the release of vesicles from the trans-Golgi network (By similarity). Regulates the expression of SLC5A1 in a tissue-specific manner and is specifically involved in its regulation in the small intestine.[UniProtKB/Swiss-Prot Function]

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