Mouse Fars2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Fars2
Locus ID	69955
Kit Components	GA208377G1, Fars2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208377G2, Fars2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208377G3, Fars2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001039189, NM_024274
Synonyms	Fars1; pheRS
Summary	Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation. To a lesser extent, also catalyzes direct attachment of m-Tyr (an oxidized version of Phe) to tRNA(Phe), thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins (By similarity).[UniProtKB/Swiss-Prot Function]

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