Mouse Tprkb activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tprkb
Locus ID	69786
Kit Components	GA208323G1, Tprkb gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208323G2, Tprkb gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208323G3, Tprkb gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001170488, NM_176842, NM_001362064, NM_001362065, NM_001362066, NM_001362067
Synonyms	0610033G21Rik; 1810034M08Rik; Cgi-121; DRWMS1; mDRWMS1
Summary	Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification.[UniProtKB/Swiss-Prot Function]

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