Mouse Tnfaip8l2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tnfaip8l2
Locus ID	69769
Kit Components	GA208313G1, Tnfaip8l2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208313G2, Tnfaip8l2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208313G3, Tnfaip8l2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_027206
Synonyms	1810019A08Rik; AW610835; TIPE2
Summary	Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits JUN/AP1 and NF-kappa-B activation. Promotes Fas-induced apoptosis.[UniProtKB/Swiss-Prot Function]

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