Mouse Pir activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pir
Locus ID	69656
Kit Components	GA208263G1, Pir gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208263G2, Pir gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208263G3, Pir gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001301402, NM_027153
Synonyms	2310042L19Rik; Pirnl
Summary	Transcriptional coregulator of NF-kappa-B which facilitates binding of NF-kappa-B proteins to target kappa-B genes in a redox-state-dependent manner. May be required for efficient terminal myeloid maturation of hematopoietic cells. Has quercetin 2,3-dioxygenase activity (in vitro) (By similarity).[UniProtKB/Swiss-Prot Function]

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