Mouse Mlip activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mlip
Locus ID	69642
Kit Components	GA208259G1, Mlip gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208259G2, Mlip gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208259G3, Mlip gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_027150, NM_001368955, NM_001368956, NM_001368957, NM_001368958, NM_001368959, NM_001368960, NM_001368961, NM_001368962, NM_001368963, NM_001368964, NM_001368965, NM_001368966, NM_001368967, NM_001368968, NM_001368969, NM_001368970, NM_001368971, NM_001368972, NM_001368973, NM_001368974, NM_001368975, NM_001368976, NM_001368977, NM_001368978, NM_001368979, NM_001368980, NM_001368981, NM_001368982, NM_001368983, NM_001368984, NM_001368985, NM_001368986, NM_001368987, NM_001368988, NM_001368989
Synonyms	2310046A06Rik; AI931782; CIP
Summary	Required for precocious cardiac adaptation to stress through integrated regulation of the AKT/mTOR pathways and FOXO1. Regulates cardiac homeostasis and plays an important role in protection against cardiac hypertrophy (PubMed:26359501, PubMed:22343712, PubMed:26436652). Acts as a transcriptional cofactor, represses transactivator activity of ISL1 and MYOCD (PubMed:22343712).[UniProtKB/Swiss-Prot Function]

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