Mouse Efcab9 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Efcab9
Locus ID	69306
Kit Components	GA208124G1, Efcab9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208124G2, Efcab9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208124G3, Efcab9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_027031
Synonyms	1700007I06Rik; 4930403C08Rik
Summary	pH-dependent Ca(2+) sensor required to activate the CatSper channel, a complex involved in sperm cell hyperactivation (PubMed:31056283). Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization (PubMed:31056283). Associates with the CatSper complex via direct interaction with CATSPERZ, and senses intracellular Ca(2+) (PubMed:31056283). Together with CATSPERZ, associates with the CatSper channel pore and is required for the two-row structure of each single CatSper channel (PubMed:31056283).[UniProtKB/Swiss-Prot Function]

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