Mouse Srsf11 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Srsf11
Locus ID	69207
Kit Components	GA208090G1, Srsf11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208090G2, Srsf11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208090G3, Srsf11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001093752, NM_001093753, NM_026989, NM_001356997
Synonyms	0610009J05Rik; 2610019N13Rik; BF642805; Sfrs11
Summary	The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

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