Mouse Chrdl2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Chrdl2
Locus ID	69121
Kit Components	GA208059G1, Chrdl2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208059G2, Chrdl2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208059G3, Chrdl2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001291320, NM_133709
Synonyms	1810022C01Rik; Chl2
Summary	Implicated in tumor angiogenesis (By similarity). May inhibits BMPs activity by blocking their interaction with their receptors. Has a negative regulator effect on the cartilage formation/regeneration from immature mesenchymal cells, by preventing or reducing the rate of matrix accumulation. May play a role during myoblast and osteoblast differentiation, and maturation.[UniProtKB/Swiss-Prot Function]

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