Mouse Ecscr activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ecscr
Locus ID	68545
Kit Components	GA207851G1, Ecscr gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207851G2, Ecscr gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207851G3, Ecscr gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001033141, NM_001368651, NM_001368652
Synonyms	1110006O17Rik; ARIA
Summary	Regulates endothelial chemotaxis and tube formation (By similarity). Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2.[UniProtKB/Swiss-Prot Function]

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