Mouse Apool activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Apool
Locus ID	68117
Kit Components	GA207685G1, Apool gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207685G2, Apool gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207685G3, Apool gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001313733, NM_001313734, NM_026565
Synonyms	6720473G16Rik; 9430083G14Rik; E130106L15Rik
Summary	Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function.[UniProtKB/Swiss-Prot Function]

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