Mouse Nutf2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nutf2
Locus ID	68051
Kit Components	GA207658G1, Nutf2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207658G2, Nutf2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207658G3, Nutf2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_026532, NM_001357229, NM_001357230
Synonyms	2700067I02Rik; AI115459; AI413596; AW546000; Ntf2; Ntf3; PP15
Summary	Mediates the import of GDP-bound RAN from the cytoplasm into the nucleus which is essential for the function of RAN in cargo receptor-mediated nucleocytoplasmic transport. Thereby, plays indirectly a more general role in cargo receptor-mediated nucleocytoplasmic transport. Interacts with GDP-bound RAN in the cytosol, recruits it to the nuclear pore complex via its interaction with nucleoporins and promotes its nuclear import.[UniProtKB/Swiss-Prot Function]

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