Mouse Trap1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Trap1
Locus ID	68015
Kit Components	GA207636G1, Trap1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207636G2, Trap1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207636G3, Trap1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_026508, NR_152409
Synonyms	2410002K23Rik; HSP75
Summary	Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.[UniProtKB/Swiss-Prot Function]

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