Mouse Ube2f activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ube2f
Locus ID	67921
Kit Components	GA207587G1, Ube2f gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207587G2, Ube2f gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207587G3, Ube2f gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_026454, NM_001355761, NM_001355762, NM_001355763, NM_001355764, NR_149825
Synonyms	2510010F15Rik; AI851109
Summary	Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.[UniProtKB/Swiss-Prot Function]

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