Mouse Plpp3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Plpp3
Locus ID	67916
Kit Components	GA207584G1, Plpp3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207584G2, Plpp3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207584G3, Plpp3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_080555
Synonyms	1110003O22Rik; 2610002D05Rik; AV025606; D4Bwg0538e; D4Bwg1535e; Lpp3; Ppab2b; Ppap2b
Summary	Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P) (By similarity). Essential to the formation of the chorioallantoic placenta and extraembryonic vasculature. Also mediates gastrulation and axis formation, probably by regulating the Wnt signaling pathway.[UniProtKB/Swiss-Prot Function]

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