Mouse Coa6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Coa6
Locus ID	67892
Kit Components	GA207573G1, Coa6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207573G2, Coa6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207573G3, Coa6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_174987
Synonyms	1810063B05Rik; AI447995
Summary	Involved in the maturation of the mitochondrial respiratory chain complex IV subunit MT-CO2/COX2. Thereby, may regulate early steps of complex IV assembly. Mitochondrial respiratory chain complex IV or cytochrome c oxidase is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the matrix and as a consequence contributes to the proton gradient involved in mitochondrial ATP synthesis. May also be required for efficient formation of respiratory supercomplexes comprised of complexes III and IV.[UniProtKB/Swiss-Prot Function]

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