Mouse Gpsm1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Gpsm1
Locus ID	67839
Kit Components	GA207537G1, Gpsm1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207537G2, Gpsm1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207537G3, Gpsm1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001199146, NM_001199147, NM_153410, NM_001355574, NM_001355575, NM_001355576
Synonyms	1810037C22Rik; Ags3; AW107933
Summary	Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.[UniProtKB/Swiss-Prot Function]

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