Mouse Kat8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Kat8
Locus ID	67773
Kit Components	GA207510G1, Kat8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207510G2, Kat8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207510G3, Kat8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_026370, NM_001360699
Synonyms	2010203C02Rik; 5830450F21Rik; D7Ertd629e; MOF; Myst1
Summary	Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM. As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. That activity is less specific than the one of the MSL complex. Can also acetylate TP53/p53 at 'Lys-120'.[UniProtKB/Swiss-Prot Function]

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