Mouse Fbxo32 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Fbxo32
Locus ID	67731
Kit Components	GA207483G1, Fbxo32 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207483G2, Fbxo32 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207483G3, Fbxo32 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_026346
Synonyms	4833442G10Rik; AI430017; ATROGIN1; Gm20361; MAFbx
Summary	Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1 (By similarity).[UniProtKB/Swiss-Prot Function]

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