Mouse Ctdp1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ctdp1
Locus ID	67655
Kit Components	GA207442G1, Ctdp1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207442G2, Ctdp1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207442G3, Ctdp1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_026295
Synonyms	4930563P03Rik; AW553592
Summary	Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II. Plays a role in the exit from mitosis by dephosphorylating crucial mitotic substrates (USP44, CDC20 and WEE1) that are required for M-phase-promoting factor (MPF)/CDK1 inactivation (By similarity).[UniProtKB/Swiss-Prot Function]

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