Mouse Atg12 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Atg12
Locus ID	67526
Kit Components	GA207379G1, Atg12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207379G2, Atg12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207379G3, Atg12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_026217
Synonyms	4931423H11Rik; A330058M13Rik; Apg12l; Atg12l
Summary	Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes.[UniProtKB/Swiss-Prot Function]

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