Mouse Smc6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Smc6
Locus ID	67241
Kit Components	GA207219G1, Smc6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207219G2, Smc6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207219G3, Smc6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001324476, NM_025695, NM_001361252
Synonyms	2810489L22Rik; 3830418C19Rik; AA990493; AU018782; AW742439; mKIAA4103; SMC-6; Smc6l1
Summary	Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components (By similarity).[UniProtKB/Swiss-Prot Function]

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