Mouse Cdt1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cdt1
Locus ID	67177
Kit Components	GA207183G1, Cdt1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207183G2, Cdt1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207183G3, Cdt1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_026014
Synonyms	2610318F11Rik; AW545653; C76791; Ris2
Summary	Required for both DNA replication and mitosis. DNA replication licensing factor, required for pre-replication complex assembly. Cooperates with CDC6 and the origin recognition complex (ORC) during G1 phase of the cell cycle to promote the loading of the mini-chromosome maintenance (MCM) complex onto DNA to generate pre-replication complexes (pre-RC). Required also for mitosis by promoting stable kinetochore-microtubule attachments (By similarity). Potential oncogene (PubMed:11850834).[UniProtKB/Swiss-Prot Function]

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